Cardiovascular risk of high-versus moderate-intensity aerobic exercise in coronary heart disease patients

Rognmo, Oivind, Moholdt, Trine, Bakken, Hilde, Hole, Torstein, Molstad, Per, Myhr, Nils Erling, Grimsmo, Jostein and Wisloff, Ulrik (2012) Cardiovascular risk of high-versus moderate-intensity aerobic exercise in coronary heart disease patients. Circulation, 126 12: 1436-1440. doi:10.1161/CIRCULATIONAHA.112.123117

Author Rognmo, Oivind
Moholdt, Trine
Bakken, Hilde
Hole, Torstein
Molstad, Per
Myhr, Nils Erling
Grimsmo, Jostein
Wisloff, Ulrik
Title Cardiovascular risk of high-versus moderate-intensity aerobic exercise in coronary heart disease patients
Journal name Circulation   Check publisher's open access policy
ISSN 0009-7322
Publication date 2012-09-18
Sub-type Article (original research)
DOI 10.1161/CIRCULATIONAHA.112.123117
Open Access Status Not yet assessed
Volume 126
Issue 12
Start page 1436
End page 1440
Total pages 5
Place of publication Philadelphia, PA, United States
Publisher Lippincott Williams & Wilkins
Language eng
Formatted abstract
Backround— Exercise performed at higher relative intensities has been found to elicit a greater increase in aerobic capacity and greater cardioprotective effects than exercise at moderate intensities. An inverse association has also been detected between the relative intensity of physical activity and the risk of developing coronary heart disease, independent of the total volume of physical activity. Despite that higher levels of physical activity are effective in reducing cardiovascular events, it is also advocated that vigorous exercise could acutely and transiently increase the risk of sudden cardiac death and myocardial infarction in susceptible persons. This issue may affect cardiac rehabilitation.

Methods and Results— We examined the risk of cardiovascular events during organized high-intensity interval exercise training and moderate-intensity training among 4846 patients with coronary heart disease in 3 Norwegian cardiac rehabilitation centers. In a total of 175 820 exercise training hours during which all patients performed both types of training, we found 1 fatal cardiac arrest during moderate-intensity exercise (129 456 exercise hours) and 2 nonfatal cardiac arrests during high-intensity interval exercise (46 364 exercise hours). There were no myocardial infarctions in the data material. Because the number of high-intensity training hours was 36% of the number of moderate-intensity hours, the rates of complications to the number of patient-exercise hours were 1 per 129 456 hours of moderate-intensity exercise and 1 per 23 182 hours of high-intensity exercise.

Conclusions— The results of the current study indicate that the risk of a cardiovascular event is low after both high-intensity exercise and moderate-intensity exercise in a cardiovascular rehabilitation setting. Considering the significant cardiovascular adaptations associated with high-intensity exercise, such exercise should be considered among patients with coronary heart disease.
Keyword Coronary disease
Heart arrest
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Human Movement and Nutrition Sciences Publications
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