Pneumonia due to Chlamydia pecorum in a koala (Phascolarctos cinereus)

Mackie, J. T., Gillett, A. K., Palmieri, C., Feng, T. and Higgins, D. P. (2016) Pneumonia due to Chlamydia pecorum in a koala (Phascolarctos cinereus). Journal of Comparative Pathology, 155 4: 356-360. doi:10.1016/j.jcpa.2016.07.011


Author Mackie, J. T.
Gillett, A. K.
Palmieri, C.
Feng, T.
Higgins, D. P.
Title Pneumonia due to Chlamydia pecorum in a koala (Phascolarctos cinereus)
Formatted title
Pneumonia due to Chlamydia pecorum in a koala (Phascolarctos cinereus)
Journal name Journal of Comparative Pathology   Check publisher's open access policy
ISSN 1532-3129
0021-9975
Publication date 2016-11-01
Sub-type Article (original research)
DOI 10.1016/j.jcpa.2016.07.011
Open Access Status Not yet assessed
Volume 155
Issue 4
Start page 356
End page 360
Total pages 5
Place of publication London, United Kingdom
Publisher Elsevier
Language eng
Subject 2734 Pathology and Forensic Medicine
3400 Veterinary
Abstract Chlamydiosis is a common infectious disease of koalas (Phascolarctos cinereus), but Chlamydia spp. have not yet been demonstrated to cause pneumonia in these animals. A juvenile male koala died following an episode of respiratory disease. At necropsy examination, the lung tissue was consolidated. Microscopical lesions in the lung included pyogranulomatous bronchopneumonia, proliferation of bronchiolar and alveolar epithelium and interstitial fibrosis. Hyperplastic bronchiolar epithelial cells contained aggregates of small basophilic punctate organisms, which were confirmed as chlamydiae by transmission electron microscopy and immunohistochemistry. Real-time polymerase chain reaction identified these as Chlamydia pecorum. This report provides the best evidence to date of chlamydial infection causing pneumonia in a koala, and the first evidence that C. pecorum is capable of infecting the bronchiolar epithelium of the koala.
Formatted abstract
Chlamydiosis is a common infectious disease of koalas (Phascolarctos cinereus), but Chlamydia spp. have not yet been demonstrated to cause pneumonia in these animals. A juvenile male koala died following an episode of respiratory disease. At necropsy examination, the lung tissue was consolidated. Microscopical lesions in the lung included pyogranulomatous bronchopneumonia, proliferation of bronchiolar and alveolar epithelium and interstitial fibrosis. Hyperplastic bronchiolar epithelial cells contained aggregates of small basophilic punctate organisms, which were confirmed as chlamydiae by transmission electron microscopy and immunohistochemistry. Real-time polymerase chain reaction identified these as Chlamydia pecorum. This report provides the best evidence to date of chlamydial infection causing pneumonia in a koala, and the first evidence that C. pecorum is capable of infecting the bronchiolar epithelium of the koala.
Keyword Chlamydia
Chlamydiosis
Koala
Pneumonia
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
School of Agriculture and Food Sciences
 
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