Determinants of body composition in breastfed infants using bioimpedance spectroscopy and ultrasound skinfolds - methods comparison

Gridneva, Zoya, Hepworth, Anna R., Ward, Leigh C., Lai, Ching T., Hartmann, Peter E. and Geddes, Donna T. (2016) Determinants of body composition in breastfed infants using bioimpedance spectroscopy and ultrasound skinfolds - methods comparison. Pediatric Research, 81 3: 423-433. doi:10.1038/pr.2016.235


Author Gridneva, Zoya
Hepworth, Anna R.
Ward, Leigh C.
Lai, Ching T.
Hartmann, Peter E.
Geddes, Donna T.
Title Determinants of body composition in breastfed infants using bioimpedance spectroscopy and ultrasound skinfolds - methods comparison
Journal name Pediatric Research   Check publisher's open access policy
ISSN 0031-3998
1530-0447
Publication date 2016-11-09
Sub-type Article (original research)
DOI 10.1038/pr.2016.235
Open Access Status Not yet assessed
Volume 81
Issue 3
Start page 423
End page 433
Total pages 44
Place of publication New York, United States
Publisher Nature Publishing Group
Language eng
Subject 2735 Pediatrics, Perinatology, and Child Health
Abstract Background:Accurate, noninvasive, and inexpensive methods are required to measure infant body composition. Ultrasound (US) and bioimpedance spectroscopy (BIS) have been validated in adults and introduced in pediatric populations. The aim of this study was to evaluate the performance of both methods in determining percentage fat mass (%FM) in breastfed infants.Methods:%FM of 2, 5, 9, and 12 mo-old healthy, breastfed term infants (n = 58) was calculated using BIS-derived total body water equations and skinfold equations then compared with reference models. Skinfolds were measured with US at two and four sites (biceps, suprailiac and/or triceps, and subscapular).Results:%FM differed widely within and between methods, with the degree of variation affected by infant age/sex. Not a single method/equation was consistent with the distributions of appropriate reference values for all age/sex groups. Moderate number of matches with references values (13-24 out of 36) was seen for both types of equations. High number of matches (25-36) was seen for US skinfold-based equations. %FM values calculated from US and BIS were not significantly different (P = 0.35).Conclusion:Both BIS and US are practical for predicting %FM in infants. BIS calculations are highly dependent upon an appropriate set of validated age-matched equations.
Formatted abstract
Background: Accurate, non-invasive and inexpensive methods are required to measure infant body composition. Ultrasound and bioimpedance spectroscopy (BIS) have been validated in adults and introduced in pediatric populations. The aim of this study was to evaluate the performance of both methods in determining percentage fat mass (%FM) in breastfed infants.

Methods: %FM of 2, 5, 9 and 12 month-old healthy, breastfed term infants (n = 58) was calculated using BIS-derived total body water equations and skinfold equations and compared to reference models. Skinfolds were measured with ultrasound at two and four sites (biceps, suprailiac and/or triceps, subscapular).

Results: %FM differed widely within and between methods, with the degree of variation affected by infant age/sex. No one method/equation was consistent with the distributions of appropriate reference values for all age/sex groups. Moderate number of matches with references values (13 – 24 out of 36) was seen for both types of equations. High number of matches (25 – 36) was seen for ultrasound skinfold-based equations. %FM values calculated from ultrasound and BIS were not significantly different (P = 0.35).

Conclusions: Both BIS and ultrasound are practical for predicting %FM in infants. BIS calculations are highly dependent upon an appropriate set of validated age-matched equations.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
School of Chemistry and Molecular Biosciences
 
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Created: Fri, 18 Nov 2016, 22:22:28 EST by Mrs Louise Nimwegen on behalf of School of Chemistry & Molecular Biosciences