The ICU mobility scale has construct and predictive validity and is responsive. A multicenter observational study

Tipping, Claire J., Bailey, Michael J., Bellomo, Rinaldo, Berney, Susan, Buhr, Heidi, Denehy, Linda, Harrold, Meg, Holland, Anne, Higgins, Alisa M., Iwashyna, Theodore J., Needham, Dale, Presneill, Jeff, Saxena, Manoj, Skinner, Elizabeth H., Webb, Steve, Young, Paul, Zanni, Jennifer and Hodgson, Carol L. (2016) The ICU mobility scale has construct and predictive validity and is responsive. A multicenter observational study. Annals of the American Thoracic Society, 13 6: 887-893. doi:10.1513/AnnalsATS.201510-717OC

Author Tipping, Claire J.
Bailey, Michael J.
Bellomo, Rinaldo
Berney, Susan
Buhr, Heidi
Denehy, Linda
Harrold, Meg
Holland, Anne
Higgins, Alisa M.
Iwashyna, Theodore J.
Needham, Dale
Presneill, Jeff
Saxena, Manoj
Skinner, Elizabeth H.
Webb, Steve
Young, Paul
Zanni, Jennifer
Hodgson, Carol L.
Title The ICU mobility scale has construct and predictive validity and is responsive. A multicenter observational study
Journal name Annals of the American Thoracic Society   Check publisher's open access policy
ISSN 2325-6621
Publication date 2016-06-01
Year available 2016
Sub-type Article (original research)
DOI 10.1513/AnnalsATS.201510-717OC
Open Access Status Not yet assessed
Volume 13
Issue 6
Start page 887
End page 893
Total pages 7
Place of publication New York, NY United States
Publisher American Thoracic Society
Language eng
Formatted abstract
Rationale: The ICU Mobility Scale (IMS) is a measure of mobility milestones in critically ill patients.

Objectives: This study aimed to determine the validity and responsiveness of the IMS from a prospective cohort study of adults admitted to the intensive care unit (ICU).

Methods: Construct and predictive validity were assessed by comparing IMS values at ICU discharge in 192 patients to other variables using Spearman rank correlation coefficient, Mann-Whitney U tests, and logistic regression. Responsiveness was assessed using change over time, effect size, floor and ceiling effects, and percentage of patients showing change.

Measurements and Main Results: The IMS at ICU discharge demonstrated a moderate correlation with muscle strength (r = 0.64, P < 0.001). There was a significant difference between the IMS at ICU discharge in patients with ICU-acquired weakness (median, 4.0; interquartile range, 3.0–5.0) compared with patients without (median, 8.0; interquartile range, 5.0–8.0; P < 0.001). Increasing IMS values at ICU discharge were associated with survival to 90 days (odds ratio [OR], 1.38; 95% confidence interval [CI], 1.14–1.66) and discharge home (OR, 1.16; 95% CI, 1.02–1.32) but not with return to work at 6 months (OR, 1.09; 95% CI, 0.92–1.28). The IMS was responsive with a significant change from study enrollment to ICU discharge (d = 0.8, P < 0.001), with IMS values increasing in 86% of survivors during ICU admission. No substantial floor (14% scored 0) or ceiling (4% scored 10) effects were present at ICU discharge.

Conclusions: Our findings support the validity and responsiveness of the IMS as a measure of mobility in the ICU.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Mater Research Institute-UQ (MRI-UQ)
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Created: Thu, 17 Nov 2016, 21:53:49 EST by Julia McCabe on behalf of School of Medicine