Effects of prolonged and acute muscle pain on the force control strategy during isometric contractions

Mista, Christian A., Bergin, Michael J. G., Hirata, Rogerio P., Christensen, Steffan W., Tucker, Kylie, Hodges, Paul and Graven-Nielsen, Thomas (2016) Effects of prolonged and acute muscle pain on the force control strategy during isometric contractions. Journal of Pain, 17 10: 1116-1125. doi:10.1016/j.jpain.2016.06.013

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Author Mista, Christian A.
Bergin, Michael J. G.
Hirata, Rogerio P.
Christensen, Steffan W.
Tucker, Kylie
Hodges, Paul
Graven-Nielsen, Thomas
Title Effects of prolonged and acute muscle pain on the force control strategy during isometric contractions
Journal name Journal of Pain   Check publisher's open access policy
ISSN 1528-8447
1526-5900
Publication date 2016-10-01
Sub-type Article (original research)
DOI 10.1016/j.jpain.2016.06.013
Open Access Status File (Author Post-print)
Volume 17
Issue 10
Start page 1116
End page 1125
Total pages 10
Place of publication Philadelphia, PA, United States
Publisher Churchill Livingstone
Collection year 2017
Language eng
Formatted abstract
Musculoskeletal pain is associated with multiple adaptions in movement control. This study aimed to determine whether changes in movement control acquired during acute pain are maintained over days of pain exposure. On day 0, the extensor carpi radialis brevis muscle of healthy participants was injected with nerve growth factor (NGF) to induce persistent movement-evoked pain (n = 13) or isotonic saline as a control (n = 13). On day 2, short-lasting pain was induced by injection of hypertonic saline into extensor carpi radialis brevis muscles of all participants. Three-dimensional force components were recorded during submaximal isometric wrist extensions on day 0, day 4, and before, during, and after saline-induced pain on day 2. Standard deviation (variation of task-related force) and total excursion of center of pressure (variation of force direction) were assessed. Maximal movement-evoked pain was 3.3 ± .4 (0–10 numeric scale) in the NGF-group on day 2 whereas maximum saline-induced pain was 6.8 ± .3 cm (10-cm visual analog scale). The difference in centroid position of force direction relative to day 0 was greater in the NGF group than in the control group (P < .05) on day 2 (before saline-induced pain) and day 4, reflecting changes in tangential force direction used to achieve the task. During saline-induced pain in both groups, tangential and task-related force variation was greater than before and after saline-induced pain (P < .05).

Perspective: Persistent movement-evoked pain changes force direction from the pain-free direction. Acute pain leads to increased variation in force direction irrespective of persistent movement-evoked pain preceding the acutely painful event. These differences provide novel insight into the search for and consolidation of new motor strategies in the presence of pain.
Keyword Force
Muscle pain
NGF
Persistent pain
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
School of Biomedical Sciences Publications
School of Health and Rehabilitation Sciences Publications
 
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