Reduced maximal force during acute anterior knee pain is associated with deficits in voluntary muscle activation

Salomoni, Sauro, Tucker, Kylie, Hug, François, McPhee, Megan and Hodges, Paul (2016) Reduced maximal force during acute anterior knee pain is associated with deficits in voluntary muscle activation. PLoS ONE, 11 8: e0161487. doi:10.1371/journal.pone.0161487


Author Salomoni, Sauro
Tucker, Kylie
Hug, François
McPhee, Megan
Hodges, Paul
Title Reduced maximal force during acute anterior knee pain is associated with deficits in voluntary muscle activation
Journal name PLoS ONE   Check publisher's open access policy
ISSN 1932-6203
Publication date 2016-08-25
Sub-type Article (original research)
DOI 10.1371/journal.pone.0161487
Open Access Status DOI
Volume 11
Issue 8
Start page e0161487
Total pages 14
Place of publication San Francisco, CA, United States
Publisher Public Library of Science
Language eng
Subject 1300 Biochemistry, Genetics and Molecular Biology
1100 Agricultural and Biological Sciences
Abstract Although maximal voluntary contraction (MVC) force is reduced during pain, studies using interpolated twitch show no consistent reduction of voluntary muscle drive. The present study aimed to test if the reduction in MVC force during acute experimental pain could be explained by increased activation of antagonist muscles, weak voluntary activation at baseline, or changes in force direction. Twenty-two healthy volunteers performed maximal voluntary isometric knee extensions before, during, and after the effects of hypertonic (pain) and isotonic (control) saline injections into the infrapatellar fat pad. The MVC force, voluntary activation, electromyographic (EMG) activity of agonist, antagonist, and auxiliary (hip) muscles, and pain cognition and anxiety scores were recorded. MVC force was 9.3% lower during pain than baseline (p < 0.001), but there was no systematic change in voluntary activation. Reduced MVC force during pain was variable between participants (SD: 14%), and was correlated with reduced voluntary activation (r = 0.90), baseline voluntary activation (r = - 0.62), and reduced EMG amplitude of agonist and antagonist muscles (all r > 0.52), but not with changes in force direction, pain or anxiety scores. Hence, reduced MVC force during acute pain was mainly explained by deficits in maximal voluntary drive.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
School of Biomedical Sciences Publications
School of Health and Rehabilitation Sciences Publications
 
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