The mouse model of oxygen-induced retinopathy: A suitable animal model for angiogenesis research

Gole, GA, Browning, J and Elts, SM (1990) The mouse model of oxygen-induced retinopathy: A suitable animal model for angiogenesis research. Documenta Ophthalmologica, 74 3: 163-169. doi:10.1007/BF02482605


Author Gole, GA
Browning, J
Elts, SM
Title The mouse model of oxygen-induced retinopathy: A suitable animal model for angiogenesis research
Journal name Documenta Ophthalmologica   Check publisher's open access policy
ISSN 0012-4486
Publication date 1990-01-01
Sub-type Article (original research)
DOI 10.1007/BF02482605
Volume 74
Issue 3
Start page 163
End page 169
Total pages 7
Publisher Kluwer Academic Publishers
Language eng
Subject 2731 Ophthalmology
2809 Sensory Systems
2737 Physiology (medical)
Abstract Newborn mice exposed to high (>98%) ambient oxygen during the newborn period and subsequently removed to room air will develop a proliferative retinopathy which mimics the neovascular component of acute retinopathy of prematurity. In this paper, we report preliminary ultrastructural findings on the vitreous new vessels in the mouse model of oxygen-induced retinopathy, and argue that the model is appropriate for research on non surgical treatments for ROP in particular and angiogenesis in general.
Keyword angiogenesis
mouse
oxygen-induced retinopathy
retinopathy of prematurity
ultrastructure
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
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Citation counts: TR Web of Science Citation Count  Cited 19 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 18 times in Scopus Article | Citations
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