Bovine ocular squamous-cell carcinoma: Lymphocyte response to phytohaemagglutinin and tumour antigen

Jennings P.A., Lavin M.F., Hughes D.J. and Spradbrow P.B. (1979) Bovine ocular squamous-cell carcinoma: Lymphocyte response to phytohaemagglutinin and tumour antigen. British Journal of Cancer, 40 4: 608-614. doi:10.1038/bjc.1979.226


Author Jennings P.A.
Lavin M.F.
Hughes D.J.
Spradbrow P.B.
Title Bovine ocular squamous-cell carcinoma: Lymphocyte response to phytohaemagglutinin and tumour antigen
Journal name British Journal of Cancer   Check publisher's open access policy
ISSN 1532-1827
Publication date 1979-01-01
Sub-type Article (original research)
DOI 10.1038/bjc.1979.226
Volume 40
Issue 4
Start page 608
End page 614
Total pages 7
Subject 1306 Cancer Research
2730 Oncology
Abstract The presence of ocular squamous-cell carcinomas in cattle was associated with significantly lower blastogenic response of peripheral-blood cultures to PHA than that of age-matched control cattle. The difference in blastogenic response was more marked when the external diameter of the tumour exceeded 2 cm. Cattle with aquamous-cell carcinomas had cell-mediated immunity against tumour extracts, as measured by the leucocyte adherence inhibition (LAI) microassay. The LAI reaction against tumour extracts was directly proportional to the general level of cell-mediated immunity as demonstrated by the lymphoproliferative response to PHA.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
 
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Created: Tue, 04 Oct 2016, 11:58:38 EST by System User