THE DENSITY OF ADRENERGIC NERVES AT VARIOUS LEVELS IN THE GUINEA‐PIG LUNG

O'Donnell S.R., Saar N. and Wood L.J. (1978) THE DENSITY OF ADRENERGIC NERVES AT VARIOUS LEVELS IN THE GUINEA‐PIG LUNG. Clinical and Experimental Pharmacology and Physiology, 5 4: 325-332. doi:10.1111/j.1440-1681.1978.tb00681.x


Author O'Donnell S.R.
Saar N.
Wood L.J.
Title THE DENSITY OF ADRENERGIC NERVES AT VARIOUS LEVELS IN THE GUINEA‐PIG LUNG
Journal name Clinical and Experimental Pharmacology and Physiology   Check publisher's open access policy
ISSN 1440-1681
Publication date 1978-01-01
Sub-type Article (original research)
DOI 10.1111/j.1440-1681.1978.tb00681.x
Volume 5
Issue 4
Start page 325
End page 332
Total pages 8
Subject 1314 Physiology
3004 Pharmacology
2737 Physiology (medical)
Abstract 1. Guinea‐pig tracheal and lung segments were systematically examined for adrenergic nerves using the fluorescence histochemical technique. Fluorescence in nerves was enhanced with α‐methylnoradrenaline or by pretreating the animals with nialamide. 2. There was a progressive decrease in density of fluorescent fibres in airway smooth muscle from the laryngeal end of the trachea, which was densely innervated, to the bronchioles, which contained only occasional fibres. This was despite obvious fluorescence in blood vessels in the lung. 3. It is suggested that, if adrenergic nerves are involved in reflex bronchodilatation in this species, they directly control larger airways and other factors, e.g. non‐adrenergic inhibitory nerves, may be important in the control of smaller airways. Copyright
Keyword adrenergic nerves
fluorescence histochemistry
guinea‐pig
lung
Q-Index Code C1
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
 
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Created: Tue, 27 Sep 2016, 13:43:01 EST by System User