Monocular and binocular contributions to oculomotor plasticity

Maiello, Guido, Harrison, William J. and Bex, Peter J. (2016) Monocular and binocular contributions to oculomotor plasticity. Scientific Reports, 6 31861. doi:10.1038/srep31861


Author Maiello, Guido
Harrison, William J.
Bex, Peter J.
Title Monocular and binocular contributions to oculomotor plasticity
Journal name Scientific Reports   Check publisher's open access policy
ISSN 2045-2322
Publication date 2016-08-18
Sub-type Article (original research)
DOI 10.1038/srep31861
Open Access Status DOI
Volume 6
Start page 31861
Total pages 7
Place of publication London, United Kingdom
Publisher Nature Publishing Group
Language eng
Subject 1000 General
Abstract Most eye movements in the real-world redirect the foveae to objects at a new depth and thus require the co-ordination of monocular saccade amplitudes and binocular vergence eye movements. Additionally to maintain the accuracy of these oculomotor control processes across the lifespan, ongoing calibration is required to compensate for errors in foveal landing positions. Such oculomotor plasticity has generally been studied under conditions in which both eyes receive a common error signal, which cannot resolve the long-standing debate regarding whether both eyes are innervated by a common cortical signal or by a separate signal for each eye. Here we examine oculomotor plasticity when error signals are independently manipulated in each eye, which can occur naturally owing to aging changes in each eye's orbit and extra-ocular muscles, or in oculomotor dysfunctions. We find that both rapid saccades and slow vergence eye movements are continuously recalibrated independently of one another and corrections can occur in opposite directions in each eye. Whereas existing models assume a single cortical representation of space employed for the control of both eyes, our findings provide evidence for independent monoculomotor and binoculomotor plasticities and dissociable spatial mapping for each eye.
Formatted abstract
Most eye movements in the real-world redirect the foveae to objects at a new depth and thus require the co-ordination of monocular saccade amplitudes and binocular vergence eye movements. Additionally to maintain the accuracy of these oculomotor control processes across the lifespan, ongoing calibration is required to compensate for errors in foveal landing positions. Such oculomotor plasticity has generally been studied under conditions in which both eyes receive a common error signal, which cannot resolve the long-standing debate regarding whether both eyes are innervated by a common cortical signal or by a separate signal for each eye. Here we examine oculomotor plasticity when error signals are independently manipulated in each eye, which can occur naturally owing to aging changes in each eye's orbit and extra-ocular muscles, or in oculomotor dysfunctions. We find that both rapid saccades and slow vergence eye movements are continuously recalibrated independently of one another and corrections can occur in opposite directions in each eye. Whereas existing models assume a single cortical representation of space employed for the control of both eyes, our findings provide evidence for independent monoculomotor and binoculomotor plasticities and dissociable spatial mapping for each eye.
Q-Index Code C1
Q-Index Status Provisional Code
Grant ID R01EY021553
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
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Queensland Brain Institute Publications
 
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