The regulation of bicarbonate reabsorption - The role of arterial pH, {Mathematical expression} and plasma bicarbonate concentration

Slaughter B.D., Osiecki H.S., Cross R.B., Budtz-Olsen O. and Jedrzejczyk H. (1974) The regulation of bicarbonate reabsorption - The role of arterial pH, {Mathematical expression} and plasma bicarbonate concentration. Pflügers Archiv European Journal of Physiology, 349 1: 29-40. doi:10.1007/BF00587914


Author Slaughter B.D.
Osiecki H.S.
Cross R.B.
Budtz-Olsen O.
Jedrzejczyk H.
Title The regulation of bicarbonate reabsorption - The role of arterial pH, {Mathematical expression} and plasma bicarbonate concentration
Journal name Pflügers Archiv European Journal of Physiology   Check publisher's open access policy
ISSN 0031-6768
Publication date 1974-01-01
Sub-type Article (original research)
DOI 10.1007/BF00587914
Open Access Status
Volume 349
Issue 1
Start page 29
End page 40
Total pages 12
Publisher Springer-Verlag
Subject 1314 Physiology
Abstract Renal reabsorption of bicarbonate was examined in Merino ewes. In all experiments the bicarbonate reabsorption was directly related to that of sodium. When the rate of bicarbonate reabsorption was expressed as the ratio of bicarbonate over sodium reabsorption, no tubular maximum for bicarbonate could be demonstrated. Arterial pH or {Mathematical expression} did not affect the reabsorption of bicarbonate except through alterations in the plasma bicarbonate concentration. The ratio of bicarbonate over sodium reabsorption was directly proportional to the plasma concentration of bicarbonate over a wide range. This evidence suggests that the ionic reabsorption of bicarbonate constitutes a major part of total bicarbonate reabsorption. It does not, however, exclude a contribution from an active hydrogen ion secretory process, as the kinetic properteis of such a process are as yet undetermined.
Keyword Kidney
Plasma [HCO3 -]
Tubular Maximum
Tubular Reabsorption
{Mathematical expression}
Q-Index Code C1
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
 
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Created: Tue, 13 Sep 2016, 12:01:45 EST by System User