Induced hypocalcaemia in ruminants: Changes in some parameters of circulatory function

Barzanji A.A.H. and Daniel R.C.W. (1988) Induced hypocalcaemia in ruminants: Changes in some parameters of circulatory function. British Veterinary Journal, 144 3: 229-235. doi:10.1016/0007-1935(88)90106-6


Author Barzanji A.A.H.
Daniel R.C.W.
Title Induced hypocalcaemia in ruminants: Changes in some parameters of circulatory function
Journal name British Veterinary Journal   Check publisher's open access policy
ISSN 0007-1935
Publication date 1988-01-01
Sub-type Article (original research)
DOI 10.1016/0007-1935(88)90106-6
Volume 144
Issue 3
Start page 229
End page 235
Total pages 7
Subject 3400 Veterinary
Abstract Hypocalcaemia was induced in cows and sheep by Na2EDTA infusion and the plasma calcium concentrations then related to cardiac output, stroke volume, mean right atrial pressure, mean right ventricular pressure, mean pulmonary arterial pressure, right ventricular work against pulmonary arterial pressure and pulmonary vascular resistance. It was found that for a fall in plasma calcium concentration of 1 mmol/l in cows cardiac output was reduced by 38 ml/kg bwt/min, stroke volume by 0·64 ml/kg bwt/beat, mean right atrial pressure increased by 7·6 mmHg, mean right ventricular pressure increased by 5·9 mmHg, mean pulmonary arterial pressure increased by 6·8 mmHg, right ventricular work against pulmonary arterial pressure decreased by 28·1 J/min and pulmonary vascular resistance increased by 41 dyn·cm5/s. In sheep cardiac output was reduced by 37·3 ml/kg bwt and stroke volume by 0·48 ml/kg bwt/beat for a fall in plasma calcium concentration of 1 mmol/1. The significance of these findings in hypocalcaemic disorders is discussed.
Q-Index Code C1
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
 
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