Repetitive loading, in vivo, of the tibia and femora of rats: Effects of a single bout of treadmill running

Forwood M.R. and Parker A.W. (1992) Repetitive loading, in vivo, of the tibia and femora of rats: Effects of a single bout of treadmill running. Calcified Tissue International, 50 2: 193-196. doi:10.1007/BF00298800


Author Forwood M.R.
Parker A.W.
Title Repetitive loading, in vivo, of the tibia and femora of rats: Effects of a single bout of treadmill running
Journal name Calcified Tissue International   Check publisher's open access policy
ISSN 0171-967X
Publication date 1992-01-01
Sub-type Article (original research)
DOI 10.1007/BF00298800
Volume 50
Issue 2
Start page 193
End page 196
Total pages 4
Publisher Springer-Verlag
Subject 1310 Endocrinology
Abstract The presence of microdamage in the tibiae and femora of rats following repetitive loading in vivo was investigated by subjecting 48 male rats, aged 12 weeks, to treadmill running (26.8 m.min-1 on 10% grade) for 0.56 hours (5,000 cycles, E1), 1.13 hours, (10,000 cycles, E2), 2.27 hours (20,000 cycles, E3), and 3.4 hours (30,000 cycles, E4) with Group C as control. Following exercise, tibiae and femora were excised and the right limbs were tested in torsion at 180°.sec-1. Transverse sections were cut from the proximal, mid- and distal diaphysis of left tibiae and femora, bulk stained in basic fuchsin, cut to 50 μm thick, and examined for the presence of microdamage. Following these periods of loading, tibiae and femora showed no evidence of microdamage initiation, as evidenced by light microscopy, or corresponding alterations in mechanical properties. It was concluded that the magnitude of loading produced by single bouts of intensive exercise, which encompassed up to 30,000 loading cycles, was insufficient to initiate fatigue microdamage in tibiae or femora of rats.
Keyword Bone
Exercise
Fatigue microdamage
Mechanical properties
Q-Index Code C1
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
 
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