Influence of ethanol on fatty acid composition of phospholipids in cultured neurons

Morrisson M., Wilce P.A. and Shanley B.C. (1984) Influence of ethanol on fatty acid composition of phospholipids in cultured neurons. Biochemical and Biophysical Research Communications, 122 2: 516-521. doi:10.1016/S0006-291X(84)80063-7


Author Morrisson M.
Wilce P.A.
Shanley B.C.
Title Influence of ethanol on fatty acid composition of phospholipids in cultured neurons
Journal name Biochemical and Biophysical Research Communications   Check publisher's open access policy
ISSN 1090-2104
Publication date 1984-07-31
Sub-type Article (original research)
DOI 10.1016/S0006-291X(84)80063-7
Volume 122
Issue 2
Start page 516
End page 521
Total pages 6
Subject 1303 Specialist Studies in Education
1304 Biophysics
1312 Molecular Biology
Abstract Animals chronically exposed to ethanol show changes in neural membrane lipids which may underlie the development of tolerance and physical dependence. The object of this study was to investigate changes in the fatty acid composition of neuronal phospholipids cultured in the presence of ethanol (66 or 110 mM) for periods up to 7 days. Decreases were observed in the percentage of individual and total saturated fatty acids, while the double bond index: total saturated fatty acid ratio, increased. These changes do not support the hypothesis that neural membrane lipid composition changes to counteract the fluidizing action of ethanol.
Q-Index Code C1
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
 
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Created: Tue, 13 Sep 2016, 10:25:01 EST by System User