Sciatic axotomy compromises axonal transport of transganglionic tracer BSI-B4 from the soma to the central terminals of C fibre afferents

Kitchener P.D., Wilson P. and Snow P.J. (1994) Sciatic axotomy compromises axonal transport of transganglionic tracer BSI-B4 from the soma to the central terminals of C fibre afferents. Neuroscience Letters, 166 2: 121-125. doi:10.1016/0304-3940(94)90466-9


Author Kitchener P.D.
Wilson P.
Snow P.J.
Title Sciatic axotomy compromises axonal transport of transganglionic tracer BSI-B4 from the soma to the central terminals of C fibre afferents
Journal name Neuroscience Letters   Check publisher's open access policy
ISSN 0304-3940
Publication date 1994-01-31
Sub-type Article (original research)
DOI 10.1016/0304-3940(94)90466-9
Volume 166
Issue 2
Start page 121
End page 125
Total pages 5
Subject 2800 Neuroscience
Abstract The C afferent specific lectin BSI-B4 was used to examine the effects of sciatic axotomy on axonal transport by the C afferent subpopulation. From about 4 days after sciatic nerve lesion, BSI-B4 injected into the peripheral nerve is transported only as far as the neuronal cell bodies in the dorsal root ganglion. The previous demonstrations of Aβ afferent terminal sprouting into lamina II, and the atrophy of lamina II terminals, in response to sciatic lesions may be related to the inability of C afferents to maintain transganglionic transport.
Keyword Axonal transport
Collateral sprouting
Dorsal root ganglion
Lectin
Spinal cord
Transganglionic degeneration
Q-Index Code C1
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
 
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Created: Tue, 13 Sep 2016, 10:23:53 EST by System User