The comparative tuberculin test in guinea pigs using PPD extracts prepared from mycobacteria killed with phenol

CHOI C.S., FROST A.J. and FRANCIS J. (1982) The comparative tuberculin test in guinea pigs using PPD extracts prepared from mycobacteria killed with phenol. Australian Veterinary Journal, 59 6: 183-186. doi:10.1111/j.1751-0813.1982.tb16001.x


Author CHOI C.S.
FROST A.J.
FRANCIS J.
Title The comparative tuberculin test in guinea pigs using PPD extracts prepared from mycobacteria killed with phenol
Journal name Australian Veterinary Journal   Check publisher's open access policy
ISSN 1751-0813
Publication date 1982-01-01
Sub-type Article (original research)
DOI 10.1111/j.1751-0813.1982.tb16001.x
Open Access Status
Volume 59
Issue 6
Start page 183
End page 186
Total pages 4
Subject 2700 Medicine
3400 Veterinary
Abstract Summary. Purified‐protein‐derivative (PPD) extracts were prepared from Mycobacterium tuberculosis (PPD‐S), M. bovis (PPD‐BS), M. avium (PPD‐A) and M. kansasii (PPD‐K), after killing the cultures with phenol. The reactions were assessed in guinea pigs sensitised to a range of mycobacteria, with a view to selecting a suitable pairing of the extracts to distinguish sensitivity due to M. tuberculosis or M. bovis from that due to other mycobacteria. Sensitisation induced by M. bovis was best distinguished from others using PPD‐S and PPD‐A; for sensitisation by atypical mycobacteria, PPD‐BS was better than PPD‐S, used with either PPD‐K or PPD‐A, PPD‐BS was more specific than PPD‐S. Using PPD‐BS, PPD‐A and PPD‐K in a comparative test, 3 groups were recognised: those sensitive to M. bovis or M. tuberculosis (greatest reaction was to PPD‐BS); those sensitive to M. avium, M. Intracellulare and M. scrofulaceum (greatest reaction was to PPD‐A); those sensitive to M. kansasii, M. marium, M. gordonae and M. fortuitum (greatest reaction was to PPD‐K). Copyright
Q-Index Code C1
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
 
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Created: Tue, 06 Sep 2016, 13:49:38 EST by System User