FATTY ACID COMPOSITION OF TISSUE LIPIDS IN CHOLINE DEFICIENT RATS

Chahl J.S. and Kratzing C.C. (1973) FATTY ACID COMPOSITION OF TISSUE LIPIDS IN CHOLINE DEFICIENT RATS. Quarterly Journal of Experimental Physiology and Cognate Medical Sciences, 58 3: 275-284. doi:10.1113/expphysiol.1973.sp002215


Author Chahl J.S.
Kratzing C.C.
Title FATTY ACID COMPOSITION OF TISSUE LIPIDS IN CHOLINE DEFICIENT RATS
Journal name Quarterly Journal of Experimental Physiology and Cognate Medical Sciences   Check publisher's open access policy
ISSN 1469-445X
Publication date 1973-07-16
Sub-type Article (original research)
DOI 10.1113/expphysiol.1973.sp002215
Volume 58
Issue 3
Start page 275
End page 284
Total pages 10
Subject 1314 Physiology
Abstract Rats fed a choline deficient diet for three weeks had up to 38% of their liver weight in lipids, compared with 6·5% in choline supplemented controls. This large increase in liver lipids was due to an accumulation of triglycerides, whose fatty acid composition was not altered in choline deficiency although the plasma triglyceride concentration of stearic acid was increased and that of oleic acid was decreased. In choline‐deficient rats, the concentration of arachidonic acid was decreased in liver phospholipids while that of docosapolyenoic acids was increased. There were more widespread changes in the cholesterol ester fatty acids of liver and plasma in choline deficient rats. It is proposed that selective impairment of transport of lipid species, depending on fatty acid composition, occurs in choline deficiency.
Q-Index Code C1
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
 
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Created: Tue, 06 Sep 2016, 11:49:13 EST by System User