The biologic significance of neutrophil regulatory mechanisms

Thong Y.H. (1982) The biologic significance of neutrophil regulatory mechanisms. Medical Hypotheses, 8 3: 243-248. doi:10.1016/0306-9877(82)90119-0

Author Thong Y.H.
Title The biologic significance of neutrophil regulatory mechanisms
Journal name Medical Hypotheses   Check publisher's open access policy
ISSN 0306-9877
Publication date 1982-01-01
Sub-type Article (original research)
DOI 10.1016/0306-9877(82)90119-0
Volume 8
Issue 3
Start page 243
End page 248
Total pages 6
Language eng
Subject 1309 Developmental Biology
2700 Medicine
3002 Drug Discovery
Abstract Self-regulation and feedback control are essential features of most complex biological systems. Neutrophil leukocytes possess potent oxidative and lysomal products for the killing of invading microbes. These toxic products are also capable of causing auto-oxidative injury and tissue damage. Indeed, neutrophils have been implicated as mediators of tissue injury in a number of autoimmune and inflammatory disorders. It is proposed that a sophisticated and complex regulatory mechanism for neutrophil function is operative in healthy individuals. Much of the evidence for this is tentative and fragmentary, but a logical framework is beginning to emerge.
Q-Index Code C1
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import
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Citation counts: TR Web of Science Citation Count  Cited 2 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 2 times in Scopus Article | Citations
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