Demonstration of vascular permeability changes in cattle infected with bovine ephemeral fever virus

Young P.L. and Spradbrow P.B. (1990) Demonstration of vascular permeability changes in cattle infected with bovine ephemeral fever virus. Journal of Comparative Pathology, 102 1: 55-62. doi:10.1016/S0021-9975(08)80007-2


Author Young P.L.
Spradbrow P.B.
Title Demonstration of vascular permeability changes in cattle infected with bovine ephemeral fever virus
Journal name Journal of Comparative Pathology   Check publisher's open access policy
ISSN 0021-9975
Publication date 1990-01-01
Sub-type Article (original research)
DOI 10.1016/S0021-9975(08)80007-2
Volume 102
Issue 1
Start page 55
End page 62
Total pages 8
Subject 1103 Clinical Sciences
Abstract Five cattle infected with bovine ephemeral fever virus were necropsied on the day after onset of clinical disease, when clinical signs of lameness were most severe. Gross lesions observed included a serofibrinous polyserositis involving the synovial, pericardial, thoracic and abdominal cavities. The associated histological changes consisted primarily of oedema and an influx of neutrophils into affected tissues and fluids. In a further eight infected cattle, increases in permeability of vessels associated with serosal surfaces were demonstrated by labelling with either colloidal carbon or Evans blue. Intravenous injections of carbon provided both macroscopic and histological labelling of affected vessels. Evans blue appeared to be more sensitive than carbon but did not provide a histological marker of vascular permeability and provided labelling of tissues rather than individual vessels. The main sites of increased permeability were synovial, pericardial, thoracic and abdominal serosae.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
 
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