Carboxylesterases (EC 3.1.1). The source of variations in substrate specificity and properties of pig liver carboxylesterase

Hamilton S.E., Douglas Campbell H., de Jersey J. and Zerner B. (1975) Carboxylesterases (EC 3.1.1). The source of variations in substrate specificity and properties of pig liver carboxylesterase. Biochemical and Biophysical Research Communications, 63 4: 1146-1150. doi:10.1016/0006-291X(75)90688-9


Author Hamilton S.E.
Douglas Campbell H.
de Jersey J.
Zerner B.
Title Carboxylesterases (EC 3.1.1). The source of variations in substrate specificity and properties of pig liver carboxylesterase
Journal name Biochemical and Biophysical Research Communications   Check publisher's open access policy
ISSN 1090-2104
Publication date 1975-04-21
Sub-type Article (original research)
DOI 10.1016/0006-291X(75)90688-9
Open Access Status Not yet assessed
Volume 63
Issue 4
Start page 1146
End page 1150
Total pages 5
Subject 1303 Specialist Studies in Education
1304 Biophysics
1312 Molecular Biology
Abstract During the final stage of purification of pig liver carboxylesterase on CM-Sephadex, several enzyme activities are present in addition to the pig liver carboxylesterase reported from this laboratory (Horgan et al., 1969a). Variation in substrate specificity and specific activity of the material isolated from CM-Sephadex has been analysed with four substrates - methyl, ethyl and phenyl butyrates and butyrycholine. The sensitivity of various fractions to paraoxon, eserine and phenylmethanesulfonyl fluoride is also examined. The results support the conclusion that the variability of pig liver carboxylesterase reported from other laboratories is due to the heterogeneity here defined.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
 
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Created: Tue, 30 Aug 2016, 12:57:16 EST by System User