STUDIES ON THE PATHOGENESIS OF BOVINE EPHEMERAL FEVER

BURGESS G.W. and SPRADBROW P.B. (1977) STUDIES ON THE PATHOGENESIS OF BOVINE EPHEMERAL FEVER. Australian Veterinary Journal, 53 8: 363-368. doi:10.1111/j.1751-0813.1977.tb07952.x


Author BURGESS G.W.
SPRADBROW P.B.
Title STUDIES ON THE PATHOGENESIS OF BOVINE EPHEMERAL FEVER
Journal name Australian Veterinary Journal   Check publisher's open access policy
ISSN 1751-0813
Publication date 1977-01-01
Sub-type Article (original research)
DOI 10.1111/j.1751-0813.1977.tb07952.x
Open Access Status Not yet assessed
Volume 53
Issue 8
Start page 363
End page 368
Total pages 6
Subject 2700 Medicine
3400 Veterinary
Abstract A study of the pathogenesis of bovine ephemeral fever confirmed that the major clinical signs were fever lasting no more than 2 days, with increased respiratory rate, dyspnoea and some degree of lameness. Haematological observations revealed a neutro‐philia with a left shift and a lymphopaenia at the time of peak clinical reaction. The net result was a slight leucopaenla on the day after this reaction. The most prominent pathological changes involved the lungs and synovial joints. Pulmonary emphysema and alveolar collapse with bronchiolitis, degenerative changes in synovial membranes and increased synovial fluid were observed. Specific fluorescence indicating the presence of BEF viral antigen could be detected at the time of peak clinical response in individual cells in the lungs, spleen and lymph nodes as well as neutrophils. Before and after the peak fever some fluorescence was seen in cells which appeared to be reticular cells in the lymph nodes. Viral isolation in mice could be made from blood, lungs, spleen and lymph nodes over a period of no more than 3 days. It is postulated that viral growth takes place mainly in the reticuloendothelial cells in the lungs, spleen and lymph nodes and not in vascular endothelium or lymphoid cells. The authors wish to acknowledge Professors J. Francis and B. W. Manktelow for helpful advice and the Australian Meat Research Council for financing the project. Copyright
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
 
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