Modification of the kinetic parameters of aldolase on binding to the actin containing filaments of skeletal muscle

Walsh T.P., Clarke F.M. and Masters C.J. (1977) Modification of the kinetic parameters of aldolase on binding to the actin containing filaments of skeletal muscle. Biochemical Journal, 165 1: 165-167. doi:10.1042/bj1650165


Author Walsh T.P.
Clarke F.M.
Masters C.J.
Title Modification of the kinetic parameters of aldolase on binding to the actin containing filaments of skeletal muscle
Journal name Biochemical Journal   Check publisher's open access policy
ISSN 0264-6021
Publication date 1977-01-01
Sub-type Article (original research)
DOI 10.1042/bj1650165
Open Access Status Not yet assessed
Volume 165
Issue 1
Start page 165
End page 167
Total pages 3
Language eng
Subject 1303 Specialist Studies in Education
Abstract The kinetic parameters of fructose bisphosphate aldolase (EC 4.1.2.13) were shown to be modified on binding of the enzyme to the actin-containing filaments of skeletal muscle. Although binding to F-actin or F-actin-tropomyosin filaments results in relative minor changes in kinetic properties, binding to F-actin-tropomyosin-troponin filaments produces major alterations in the kinetic parameters, and, in addition, renders them Ca-sensitive. These observations may be relevant to an understanding of the function of this enzyme within the muscle fibre.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
 
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Created: Tue, 23 Aug 2016, 15:55:57 EST by System User