Epilepsy-from the Sakikku to hughlings Jackson

Eadie M.J. (1995) Epilepsy-from the Sakikku to hughlings Jackson. Journal of Clinical Neuroscience, 2 2: 156-162. doi:10.1016/0967-5868(95)90010-1

Author Eadie M.J.
Title Epilepsy-from the Sakikku to hughlings Jackson
Journal name Journal of Clinical Neuroscience   Check publisher's open access policy
ISSN 0967-5868
Publication date 1995-01-01
Sub-type Article (original research)
DOI 10.1016/0967-5868(95)90010-1
Open Access Status Not yet assessed
Volume 2
Issue 2
Start page 156
End page 162
Total pages 7
Subject 2728 Clinical Neurology
2737 Physiology (medical)
2808 Neurology
Abstract The phenomena of epilepsy have been known for over 3000 years. The earliest recorded account is an Akkadian text, the Sakikku, written around 1067-1046 BC. Until comparatively recent times popular belief held epilepsy to be a disorder of supernatural origin, e.g., due to demonic possession. However, there were other interpretations, e.g. a consequence of sinning or of lunar or magical influence. Such ideas began to die out only in the past 200 years. From Hippocrates (c. 400 BC) onwards, there has been a continuing alternative line of thought that epilepsy is an ordinary medical condition with a natural cause. The hypothese concerning its pathogenesis have ranged from excess phlegm in the ventricles of the brain, through boiling up of the 'vital spirits' in the brain (Paracelsus), explosion of 'animal spirits' in the centre of the brain (Willis), heightened reflex activity at a spinal (Marshall Hall) or medullary level (brown-Séquard), to Hughlings Jackson's (1870) notion of 'an occasional, an excessive, and a disorderly discharge' in part of the cerebral cortext. At the time Jackson's concepts began to be known, an effective treatment of epilepsy (potassium bromide) had recently appeared after centuries of ineffective medical measures. Since the 1860-1870 decade, epileptology has proved largely a matter of exploring the ramifications of Jackson's insights and of developing the therapeutics of the disorder in the awareness that effective treatment of possible.
Keyword Epilepsy
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
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Citation counts: TR Web of Science Citation Count  Cited 2 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 3 times in Scopus Article | Citations
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