Specific Immunodiagnosis of Hepatocellular Carcinoma by Leucocyte Adherence Inhibition

Halliday W.T., Halliday J.W., Campbell C.B., Maluish A.E. and Powell L.W. (1974) Specific Immunodiagnosis of Hepatocellular Carcinoma by Leucocyte Adherence Inhibition. British Medical Journal, 2 5915: 349-352. doi:10.1136/bmj.2.5915.349


Author Halliday W.T.
Halliday J.W.
Campbell C.B.
Maluish A.E.
Powell L.W.
Title Specific Immunodiagnosis of Hepatocellular Carcinoma by Leucocyte Adherence Inhibition
Journal name British Medical Journal   Check publisher's open access policy
ISSN 0007-1447
Publication date 1974-05-18
Sub-type Article (original research)
DOI 10.1136/bmj.2.5915.349
Volume 2
Issue 5915
Start page 349
End page 352
Total pages 4
Subject 2700 Medicine
Abstract The leucocyte adherence inhibition test provides a rapid, reliable, and specific technique for the immunodiagnosis of primary hepatocellular carcinoma (malignant hepatoma). The patient's blood leucocytes are tested in vitro for cell-mediated immunity against tumour-associated antigens and the serum is tested for blocking factor which interferes with the immunological reaction. Specific reactivity of both leucocytes and serum was consistently detected in patients with malignant hepatoma, and negative reactions were obtained in other liver diseases including secondary tumours of the liver. The test has provided positive evidence for the presence of hepatoma when more conventional methods gave doubtful or negative results. A positive result preceded the clinical appearance of tumour by up to three years in two patients.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
 
Versions
Version Filter Type
Citation counts: Scopus Citation Count Cited 26 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Tue, 16 Aug 2016, 14:37:25 EST by System User