IgG and IgE antibodies against antigens of the cat flea, Ctenocephalides felis felis, in sera of allergic and non-allergic dogs

McKeon S.E. and Opdebeeck J.P. (1994) IgG and IgE antibodies against antigens of the cat flea, Ctenocephalides felis felis, in sera of allergic and non-allergic dogs. International Journal for Parasitology, 24 2: 259-263. doi:10.1016/0020-7519(94)90035-3


Author McKeon S.E.
Opdebeeck J.P.
Title IgG and IgE antibodies against antigens of the cat flea, Ctenocephalides felis felis, in sera of allergic and non-allergic dogs
Journal name International Journal for Parasitology   Check publisher's open access policy
ISSN 0020-7519
Publication date 1994-01-01
Sub-type Article (original research)
DOI 10.1016/0020-7519(94)90035-3
Open Access Status
Volume 24
Issue 2
Start page 259
End page 263
Total pages 5
Subject 2405 Parasitology
2725 Infectious Diseases
Abstract IgG and IgE antibodies against antigens of the cat flea, Ctenocephalides felis fells, in sera of allergic and non-allergic dogs. International Journal for Parasitology 24: 259-263. Antigens from a soluble extract of cat fleas (FS) were separated using SDS-PAGE, and transferred to nitrocellulose paper. Sera from dogs shown by use of a provocative flea feeding test to be either allergic (23 dogs) or non-allergic (20 dogs) to flea bites, were used in Western blots to identify flea antigens that react with canine IgG or IgE. The sera were also tested in ELISA against FS to quantify levels of IgG and IgE antibodies. Antibodies present in the sera of both flea allergic and non-allergic dogs identified multiple anitigens. There was a great diversity of responses within each group, and there was no pattern of reactivity that distinguished dogs with flea allergy from dogs not allergic to fleas. IgG and IgE antibodies were not significantly different between the two groups of dogs. These results demonstrated that there is little association between particular antibody responses and allergic reactivity of dogs to fleas.
Keyword canine IgE
canine IgG
Ctenocephalides felis felis
Flea allergy dermatitis
immunoblots
Western blot analyses
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
 
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Created: Tue, 16 Aug 2016, 13:13:57 EST by System User