Effect of pH and nitrogen source on pigment production by Monascus purpureus

Chen M.-H. and Johns M.R. (1993) Effect of pH and nitrogen source on pigment production by Monascus purpureus. Applied Microbiology and Biotechnology, 40 1: 132-138. doi:10.1007/BF00170441


Author Chen M.-H.
Johns M.R.
Title Effect of pH and nitrogen source on pigment production by Monascus purpureus
Journal name Applied Microbiology and Biotechnology   Check publisher's open access policy
ISSN 0175-7598
Publication date 1993-01-01
Sub-type Article (original research)
DOI 10.1007/BF00170441
Volume 40
Issue 1
Start page 132
End page 138
Total pages 7
Publisher Springer-Verlag
Subject 2726 Microbiology (medical)
2404 Microbiology
1502 Banking, Finance and Investment
1305 Biotechnology
Abstract The effect of pH and nitrogen source on pigment production by Monascus purpureus 192F using glucose as the carbon and energy source, was studied in pH-controlled, batch fermentor cultures using HPLC analysis to determine individual pigment concentrations. A maximum of four pigments were detected in fungal extracts. These were the yellow pigments monascin and ankaflavin, the orange rubropunctatin and the red pigment monascorubramine. Monascorubramine was present as the major product in all instances. Fungal growth and ankaflavin synthesis were favoured at low pH (pH 4.0), whereas production of the other pigments was relatively independent of pH. The nature of the nitrogen source affected fungal growth and pigment production, independent of pH. Ammonium and peptone as nitrogen sources gave superior growth and pigment concentrations compared to nitrate. Ankaflavin was not detected in nitrate cultures. The highest red pigment production was obtained using a glucose-peptone medium at pH 6.5, due to the secretion of red pigments into the medium under these conditions.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
 
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Created: Tue, 16 Aug 2016, 12:01:12 EST by System User