Antibody responses in rats infected with Angiostrongylus cantonensis and the passive transfer of protective immunity with immune serum

Yong W.K. and Dobson C. (1982) Antibody responses in rats infected with Angiostrongylus cantonensis and the passive transfer of protective immunity with immune serum. Zeitschrift für Parasitenkunde Parasitology Research, 67 3: 329-336. doi:10.1007/BF00927668


Author Yong W.K.
Dobson C.
Title Antibody responses in rats infected with Angiostrongylus cantonensis and the passive transfer of protective immunity with immune serum
Journal name Zeitschrift für Parasitenkunde Parasitology Research   Check publisher's open access policy
ISSN 0044-3255
Publication date 1982-01-01
Sub-type Article (original research)
DOI 10.1007/BF00927668
Open Access Status Not yet assessed
Volume 67
Issue 3
Start page 329
End page 336
Total pages 8
Publisher Springer-Verlag
Subject 2405 Parasitology
2700 Medicine
Abstract Little haemagglutinating antibody was detected in the serum of rats with primary Angiostrongylus cantonensis infections until the juvenile worms left the brain and lodged in the lungs about 35 days after infection. Antibody titres reached a peak 50 days after infection and were maintained for at least a further 95 days. Increasing the infective dose of A. cantonensis larvae increased the peak antibody titres attained by the infected rats. Reinfection temporarily reduced the serum antibody titre, but later it increased and showed an anamnestic response. Reaginic antibody production was transient during primary infections; re-infection failed to stimulate further reaginic antibody production. Antiserum from immune donor rats protected recipients against A. cantonensis. The transferred immune serum suppressed anti-A. cantonensis antibody production in recipient rats.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
 
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Created: Tue, 16 Aug 2016, 11:57:17 EST by System User