Failure of a Pure Progestogen Contraceptive to Affect Serum Levels of Iron, Transferrin, Protein-bound Iodine, and Transaminase

Powell L.W., Gaffney T.J., Jacobi J.M. and Adam R. (1970) Failure of a Pure Progestogen Contraceptive to Affect Serum Levels of Iron, Transferrin, Protein-bound Iodine, and Transaminase. British Medical Journal, 3 5716: 194-195. doi:10.1136/bmj.3.5716.194


Author Powell L.W.
Gaffney T.J.
Jacobi J.M.
Adam R.
Title Failure of a Pure Progestogen Contraceptive to Affect Serum Levels of Iron, Transferrin, Protein-bound Iodine, and Transaminase
Journal name British Medical Journal   Check publisher's open access policy
ISSN 0007-1447
Publication date 1970-07-25
Sub-type Article (original research)
DOI 10.1136/bmj.3.5716.194
Volume 3
Issue 5716
Start page 194
End page 195
Total pages 2
Subject 2700 Medicine
Abstract Medroxyprogesterone acetate, a pure progestational agent which is not metabolized to oestrogen, was given to 30 women and shown to have no effect on the serum levels of iron, total iron-binding capacity, transferrin, and protein-bound iodine. Eighteen of these women had previously taken oral contraceptives of the combined oestrogen-progestogen “sequential” type, and during that time these serum levels were raised. Nevertheless, the levels all fell significantly after medroxy-progesterone acetate was given and the “sequential” oral contraceptive was stopped. In a further 12 postpartum women the serum levels did not change significantly after medroxyprogesterone acetate. These observations strongly suggest that raised plasma protein levels resulting from the administration of oral contraceptives are due to the oestrogen component.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import
 
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Created: Tue, 12 Jul 2016, 12:46:20 EST by System User