Interactions of large ions with phospholipid monolayers

Gorwyn D. and Barnes G.T. (1990) Interactions of large ions with phospholipid monolayers. Langmuir, 6 1: 222-230.

Author Gorwyn D.
Barnes G.T.
Title Interactions of large ions with phospholipid monolayers
Journal name Langmuir   Check publisher's open access policy
ISSN 0743-7463
Publication date 1990-01-01
Sub-type Article (original research)
Volume 6
Issue 1
Start page 222
End page 230
Total pages 9
Subject 1505 Marketing
1606 Political Science
Abstract Surface pressure-area isotherms of dimyristoylphosphatidylcholine, dipalmitoylphosphatidylcholine, dimyristoylphosphatidylethanolamine, and dipalmitoylphosphatidylethanolamine monolayers have been measured at 25°C on buffer solutions from pH 1.5 to 12.5, and the effects of phosphotungstate ions and of uranyl ions in the subphase have been determined. Phosphotungstate causes expansion of the monolayers at low pH values, indicating some penetration into the monolayer region and an associated increase in the bulk phase pH for protonation of the phosphate. Uranyl ions cause contraction of expanded monolayers at low pH, which is attributed to adsorption of the UO22+ drawing neighboring phospholipid molecules together. Hydrolysis of the uranyl ions at higher pH values increases their size and reduces their charge, leading to decreased effects on the monolayers. It is concluded that the use of phosphotungstic acid or uranyl acetate as a "stain" for electron microscopy could lead to significant distortions in membrane or vesicle structure.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
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Citation counts: TR Web of Science Citation Count  Cited 30 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 28 times in Scopus Article | Citations
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