Strategies for transferring mixtures of organic contaminants from aquatic environments into bioassays

Jahnke, Annika, Mayer, Philipp, Schaefer, Sabine, Witt, Gesine, Haase, Nora and Escher, Beate I. (2016) Strategies for transferring mixtures of organic contaminants from aquatic environments into bioassays. Environmental Science & Technology, 50 11: 5424-5431. doi:10.1021/acs.est.5b04687


Author Jahnke, Annika
Mayer, Philipp
Schaefer, Sabine
Witt, Gesine
Haase, Nora
Escher, Beate I.
Title Strategies for transferring mixtures of organic contaminants from aquatic environments into bioassays
Journal name Environmental Science & Technology   Check publisher's open access policy
ISSN 0013-936X
1520-5851
Publication date 2016-01-23
Year available 2016
Sub-type Article (original research)
DOI 10.1021/acs.est.5b04687
Open Access Status Not Open Access
Volume 50
Issue 11
Start page 5424
End page 5431
Total pages 8
Place of publication Washington, DC, United States
Publisher American Chemical Society
Language eng
Abstract Mixtures of organic contaminants are ubiquitous in the environment. Depending on their persistence and physicochemical properties, individual chemicals that make up the mixture partition and distribute within the environment and might then jointly elicit toxicological effects. For the assessment and monitoring of such mixtures, a variety of cell-based in vitro and low-complexity in vivo bioassays based on algae, daphnids or fish embryos are available. A very important and sometimes unrecognized challenge is how to combine sampling, extraction and dosing to transfer the mixtures from the environment into bioassays, while conserving (or re-establishing) their chemical composition at adjustable levels for concentration-effect assessment. This article outlines various strategies for quantifiable transfer from environmental samples including water, sediment, and biota into bioassays using total extraction or polymer-based passive sampling combined with either solvent spiking or passive dosing.
Keyword Freely dissolved concentrations
In vitro bioassays
Passive sampling methods
Quality trigger values
Bioaccumulative chemicals
Stress response
Risk assessment
Toxicity tests
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
National Research Centre for Environmental Toxicology Publications
 
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