Effects of nonuniform immobilized enzyme distribution in porous solid supports on the performance of a continuous reactor

Hossain Md.M. and Do D.D. (1987) Effects of nonuniform immobilized enzyme distribution in porous solid supports on the performance of a continuous reactor. The Chemical Engineering Journal, 34 2: . doi:10.1016/0300-9467(87)87011-9


Author Hossain Md.M.
Do D.D.
Title Effects of nonuniform immobilized enzyme distribution in porous solid supports on the performance of a continuous reactor
Journal name The Chemical Engineering Journal
ISSN 0300-9467
Publication date 1987-01-01
Sub-type Article (original research)
DOI 10.1016/0300-9467(87)87011-9
Volume 34
Issue 2
Total pages 1
Subject 2200 Engineering
Abstract A comprehensive model for an immobilized enzyme reactor is developed to study the performance of a nonuniform biocatalyst in a continuous stirred basket reactor. Numerical simulations have been carried out to study the influence of particle size on enzyme stability and effectiveness. The advantages of nonuniform profiles have been shown for moderate to large values of the Thiele modulus for systems obeying Michaelis-Menten kinetics. Experimental results [1] for hydrogen peroxide-immobilized enzyme on controlled-pore glass and SiAl particles were re-analyzed using the information obtained for the nonuniform distribution of immobilized enzyme. It is demonstrated that the deactivation data obtained in a continuous stirred basket reactor are followed much more closely by the nonuniformly than by the uniformly distributed enzyme model.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import
 
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