Emu oil(s): A source of non-toxic transdermal anti-inflammatory agents in aboriginal medicine

Whitehouse M.W., Turner A.G., Davis C.K.C. and Roberts M.S. (1998) Emu oil(s): A source of non-toxic transdermal anti-inflammatory agents in aboriginal medicine. Inflammopharmacology, 6 1: 1-8. doi:10.1007/s10787-998-0001-9


Author Whitehouse M.W.
Turner A.G.
Davis C.K.C.
Roberts M.S.
Title Emu oil(s): A source of non-toxic transdermal anti-inflammatory agents in aboriginal medicine
Journal name Inflammopharmacology   Check publisher's open access policy
ISSN 0925-4692
Publication date 1998-01-01
Sub-type Article (original research)
DOI 10.1007/s10787-998-0001-9
Open Access Status Not yet assessed
Volume 6
Issue 1
Start page 1
End page 8
Total pages 8
Publisher Birkhauser Verlag AG
Language eng
Subject 2403 Immunology
3004 Pharmacology
Abstract The 'oil' obtained from emu fat can be a very effective inhibitor of chronic inflammation in rats when applied dermally (with a skin penetration enhancer). Assays for this activity using the adjuvant-induced arthritis model have shown: i. Considerable variability in potency of some commercial oil samples; ii. Little or no correlation of activity with colour or linolenic acid (18:3) content of the oil; iii. Relative stability of some active oils (to heat, ageing at room temperature); iv. The bulk of the anti- inflammatory activity was present in a low triglyceride fraction; and v. Potential arthritis-suppressant/immunoregulant activity of these active fractions. These studies point to the need for more rigid quality control before considering such a (now proven) traditional medicine as a complementary therapy. Repeated applications of selected oils did not induce any of the more prominent side-effects associated with NSAIDs (e.g. platelet inhibition, gastrotoxicity) or certain anti-arthritic drugs (proteinuria, leukopenia).
Keyword Aboriginal medicine
Anti-inflammatory
Emu oil
Transdermal
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
 
Versions
Version Filter Type
Citation counts: Scopus Citation Count Cited 38 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Tue, 05 Jul 2016, 15:54:36 EST by System User