Is one motor cortex enough for two hands?

Fiori, Simona, Staudt, Martin, Pannek, Kerstin, Borghetti, Davide, Biagi, Laura, Scelfo, Danilo, Rose, Stephen E., Tosetti, Michela, Cioni, Giovanni and Guzzetta, Andrea (2015) Is one motor cortex enough for two hands?. Developmental Medicine and Child Neurology, 57 10: 977-980. doi:10.1111/dmcn.12817


Author Fiori, Simona
Staudt, Martin
Pannek, Kerstin
Borghetti, Davide
Biagi, Laura
Scelfo, Danilo
Rose, Stephen E.
Tosetti, Michela
Cioni, Giovanni
Guzzetta, Andrea
Title Is one motor cortex enough for two hands?
Journal name Developmental Medicine and Child Neurology   Check publisher's open access policy
ISSN 1469-8749
0012-1622
Publication date 2015-10-01
Year available 2015
Sub-type Article (original research)
DOI 10.1111/dmcn.12817
Open Access Status Not Open Access
Volume 57
Issue 10
Start page 977
End page 980
Total pages 4
Place of publication Chichester, West Sussex, United Kingdom
Publisher Wiley-Blackwell Publishing
Language eng
Abstract We report on a patient with mirror movements sustained by a mono-hemispheric fast control of bilateral hand muscles and normal hand function. Transcranial magnetic stimulation of the right motor cortex evoked contractions of muscles in both hands while no responses were observed from the left hemisphere. Somatosensory-evoked potentials, functional magnetic resonance, and diffusion tractography showed evidence of sensorimotor dissociation and asymmetry of corticospinal projections, suggestive of reorganization after early unilateral left brain lesion. This is the first evidence that, in certain rare conditions, good hand function is possible with ipsilateral corticospinal reorganization, supporting the role of unexplored mechanisms of motor recovery.
Formatted abstract
We report on a patient with mirror movements sustained by a mono-hemispheric fast control of bilateral hand muscles and normal hand function. Transcranial magnetic stimulation of the right motor cortex evoked contractions of muscles in both hands while no responses were observed from the left hemisphere. Somatosensory-evoked potentials, functional magnetic resonance, and diffusion tractography showed evidence of sensorimotor dissociation and asymmetry of corticospinal projections, suggestive of reorganization after early unilateral left brain lesion. This is the first evidence that, in certain rare conditions, good hand function is possible with ipsilateral corticospinal reorganization, supporting the role of unexplored mechanisms of motor recovery.
Keyword Clinical Neurology
Pediatrics
Neurosciences & Neurology
Pediatrics
Q-Index Code C1
Q-Index Status Provisional Code
Grant ID R 11-86
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: UQ Centre for Clinical Research Publications
 
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