Passive transfer of immunity with serum in mice infected with Nematospiroides dubius: In vitro effect of immune serum on larval infectivity

Dobson C. and Cayzer C.J.R. (1982) Passive transfer of immunity with serum in mice infected with Nematospiroides dubius: In vitro effect of immune serum on larval infectivity. International Journal for Parasitology, 12 5: 413-421. doi:10.1016/0020-7519(82)90070-4


Author Dobson C.
Cayzer C.J.R.
Title Passive transfer of immunity with serum in mice infected with Nematospiroides dubius: In vitro effect of immune serum on larval infectivity
Journal name International Journal for Parasitology   Check publisher's open access policy
ISSN 0020-7519
Publication date 1982-01-01
Sub-type Article (original research)
DOI 10.1016/0020-7519(82)90070-4
Volume 12
Issue 5
Start page 413
End page 421
Total pages 9
Subject 2405 Parasitology
2725 Infectious Diseases
Abstract Dobson C. and Cayzer C. J. R. 1982. Passive transfer of immunity with serum in mice infected with Nematospiroides dubius: in vitro effect of immune serum on larval infectivity. International Journal for Parasitology 12: 413-421. Incubation of Nematospiroides dubius larvae in serum in vitro induced 15% exsheathment after 3h. Larvae incubated in immune mouse serum at 37°C for 3h lost 20% of their infectivity for mice. Immune serum from donors given 1-7 concurrent or anthelmintic abbreviated infections all depressed larval infectivity to the same extent. Larvae incubated in immune sera were protected from the effects of passively transferred immune serum in mice following infection. The effects of incubation of larvae in immune serum were prolonged into the adult stages of the parasite and were seen as stunting of worms and a reduction in the male-female sex ratio of the parasites.
Keyword antibodies
immunity
in vitro effect
mice
Nematospiroides dubius
passive serum transfer
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import
 
Versions
Version Filter Type
Citation counts: Scopus Citation Count Cited 16 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Tue, 28 Jun 2016, 18:02:54 EST by System User