Isolation and genetic mapping of two novel members of the murine Wnt gene family, Wnt11 and Wnt12, and the mapping of Wnt5a and Wnt7a

Adamson M.C., Dennis C., Delaney S., Christiansen J., Monkley S., Kozak C.A. and Wainwright B. (1994) Isolation and genetic mapping of two novel members of the murine Wnt gene family, Wnt11 and Wnt12, and the mapping of Wnt5a and Wnt7a. Genomics, 24 1: 9-13. doi:10.1006/geno.1994.1575


Author Adamson M.C.
Dennis C.
Delaney S.
Christiansen J.
Monkley S.
Kozak C.A.
Wainwright B.
Title Isolation and genetic mapping of two novel members of the murine Wnt gene family, Wnt11 and Wnt12, and the mapping of Wnt5a and Wnt7a
Journal name Genomics   Check publisher's open access policy
ISSN 0888-7543
Publication date 1994-01-01
Sub-type Article (original research)
DOI 10.1006/geno.1994.1575
Volume 24
Issue 1
Start page 9
End page 13
Total pages 5
Language eng
Subject 1311 Genetics
Abstract The murine Wnt genes are implicated in the control of a variety of developmental processes. Using a PCR-based approach, we have isolated two novel members of the murine Wnt gene family, Wnt11 and Wnt12. These cDNAs display an amino acid sequence identity of between 38 and 49% with all other murine Wnts over the regions that we have isolated. In addition, two previously described Wnt genes, Wnt5a and Wnt7a, were detected in RT-PCR products. Interspecific crosses were used to demonstrate close linkage between Wnt12 and Wnt1 on Chromosome (Chr) 15. Wnt7a was mapped to mouse Chr 6, Wnt5a to the centromeric region of Chr 14, and Wnt11 to Chr7.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
 
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