Transport of O2 along a model pathway through the respiratory region of the lung

Davidson M.R. and Fitz-Gerald J.M. (1974) Transport of O2 along a model pathway through the respiratory region of the lung. Bulletin of Mathematical Biology, 36 3: 275-303. doi:10.1007/BF02461329


Author Davidson M.R.
Fitz-Gerald J.M.
Title Transport of O2 along a model pathway through the respiratory region of the lung
Journal name Bulletin of Mathematical Biology   Check publisher's open access policy
ISSN 0007-4985
Publication date 1974-01-01
Sub-type Article (original research)
DOI 10.1007/BF02461329
Open Access Status Not yet assessed
Volume 36
Issue 3
Start page 275
End page 303
Total pages 29
Publisher Kluwer Academic Publishers
Subject 1100 Agricultural and Biological Sciences
Abstract A pathway through the system of branching in the respiratory region of the lung is modelled by a circular cylinder, closed at one end, with partitions which define the component respiratory units. In this model the transport of O2 during inspiration, generated by diffusion is compared with that produced by diffusion together with convection and the importance of convection in the respiratory region in promoting oxygen uptake at the alveolar wall is discussed. For this discussion it is only necessary to consider inspiration. The equations are solved numerically for flow rates of 10, 85 and 200 liters/min. O2 uptake at the wall and curves of constant O2 concentration are shown to illustrate the influence of convection. It is found that after a 2 sec inspiration from an O2 tension of 98 mm Hg and a lung volume of 2300 ml, convection is about 12 per cent as important as diffusion at a flow rate of 85 liters/min, whereas at 10 liters/min convection is only about 0.4 per cent as important as diffusion.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
 
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Created: Tue, 28 Jun 2016, 15:36:06 EST by System User