Calcium-activated potassium channels: Multiple contributions to neuronal function

Faber, ESL and Sah, P (2003) Calcium-activated potassium channels: Multiple contributions to neuronal function. Neuroscientist, 9 3: 181-194. doi:10.1177/107385840325673


Author Faber, ESL
Sah, P
Title Calcium-activated potassium channels: Multiple contributions to neuronal function
Journal name Neuroscientist   Check publisher's open access policy
ISSN 1073-8584
Publication date 2003-01-01
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1177/107385840325673
Volume 9
Issue 3
Start page 181
End page 194
Total pages 14
Place of publication Thousand Oaks
Publisher Sage Publications Inc
Language eng
Abstract Calcium-activated potassium channels are a large family of potassium channels that are found throughout the central nervous system and in many other cell types. These channels are activated by rises in cytosolic calcium largely in response to calcium influx via voltage-gated calcium channels that open during action potentials. Activation of these potassium channels is involved in the control of a number of physiological processes from the firing properties of neurons to the control of transmitter release. These channels form the target for modulation for a range of neurotransmitters and have been implicated in the pathogenesis of neurological and psychiatric disorders. Here the authors summarize the varieties of calcium-activated potassium channels present in central neurons and their defining molecular and biophysical properties.
Keyword Clinical Neurology
Neurosciences
Sk Channel
Ahp Sahp Accommodation
Ca2+-activated K+ Channels
Ca1 Pyramidal Neurons
Long-term Potentiation
Slow Afterhyperpolarization Current
After-hyperpolarization Current
Concentration-dependent Manner
Bis-quinolinium Cyclophanes
Rabbit Hippocampal-neurons
Spike Frequency Adaptation
Adrenal Chromaffin Cells
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown
Additional Notes This document is a journal review.

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Excellence in Research Australia (ERA) - Collection
Queensland Brain Institute Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 143 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 161 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Mon, 13 Aug 2007, 23:34:30 EST