Inflammatory peptide in spinal cord: Evidence that the mediator of antidromic vasodilatation is not substance P

Chahl L.A. and Manley S.W. (1980) Inflammatory peptide in spinal cord: Evidence that the mediator of antidromic vasodilatation is not substance P. Neuroscience Letters, 18 1: 99-103. doi:10.1016/0304-3940(80)90219-0


Author Chahl L.A.
Manley S.W.
Title Inflammatory peptide in spinal cord: Evidence that the mediator of antidromic vasodilatation is not substance P
Journal name Neuroscience Letters   Check publisher's open access policy
ISSN 0304-3940
Publication date 1980-05-15
Sub-type Article (original research)
DOI 10.1016/0304-3940(80)90219-0
Volume 18
Issue 1
Start page 99
End page 103
Total pages 5
Subject 2800 Neuroscience
Abstract Extracts from rat and bovine spinal cord were found to have 300-1000 times more cutaneous oedema-inducing activity than could be attributed to their substance P-like activity estimated by assay on guinea-pig ileum. The activity on both assay systems was reduced in cord extracts from rats pretreated as neonates with capsaicin. Results of assays of fractions obtained from gel-filtration chromatography indicated that an agent, in the molecular size range for peptides, was present in spinal cord extracts, which possessed some of the properties of substance P but was not identical to it.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
 
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Created: Tue, 28 Jun 2016, 14:57:30 EST by System User