Evening primrose oil and treatment of premenstrual syndrome

Khoo S.K., Munro C. and Battistutta D. (1990) Evening primrose oil and treatment of premenstrual syndrome. Medical Journal of Australia, 153 4: 189-192.

Author Khoo S.K.
Munro C.
Battistutta D.
Title Evening primrose oil and treatment of premenstrual syndrome
Journal name Medical Journal of Australia   Check publisher's open access policy
ISSN 0025-729X
Publication date 1990-01-01
Sub-type Article (original research)
Open Access Status Not yet assessed
Volume 153
Issue 4
Start page 189
End page 192
Total pages 4
Language eng
Subject 2700 Medicine
Abstract The therapeutic effectiveness of evening primrose oil (Efamol, Vita-Glow) in the relief of 10 symptoms associated with premenstrual syndrome (PMS) as well as menstrual symptoms was studied in 38 women. The prospective trial was randomised, double-blind and placebo-controlled and was crossed-over after three cycles. Although the results showed an improvement in symptoms of PMS during the trial, no significant differences in the scoring between the active and placebo groups were found over six cycles. No "carry-over" effect of active medication was observed; the beneficial effect on all symptoms (psychological, fluid retention, breast) was rapid, the scores decreasing in the first cycle but increasing slightly at the change-over period after the third cycle, irrespective of whether the active or placebo medication was next given. These findings indicate that the improvement experienced by these women with moderate PMS was solely a placebo effect.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
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Created: Tue, 14 Jun 2016, 15:13:32 EST by System User