The effect of carbonic anhydrase inhibition on bicarbonate reabsorption

Slaughter B.D., Osiecki H.S. and Cross R.B. (1976) The effect of carbonic anhydrase inhibition on bicarbonate reabsorption. Pflügers Archiv European Journal of Physiology, 362 3: 203-208. doi:10.1007/BF00581171

Author Slaughter B.D.
Osiecki H.S.
Cross R.B.
Title The effect of carbonic anhydrase inhibition on bicarbonate reabsorption
Journal name Pflügers Archiv European Journal of Physiology   Check publisher's open access policy
ISSN 0031-6768
Publication date 1976-01-01
Sub-type Article (original research)
DOI 10.1007/BF00581171
Open Access Status
Volume 362
Issue 3
Start page 203
End page 208
Total pages 6
Publisher Springer-Verlag
Subject 1314 Physiology
Abstract Renal reabsorption of bicarbonate was studied in Merino ewes during carbonic anhydrase inhibition. Bicarbonate reabsorption was directly proportional to plasma bicarbonate concentration. No tubular maximum for bicarbonate was demonstrated. Elevation of arterial PCO2 or depression of arterial pH caused slight increases in bicarbonate reabsorption. The data suggest that bicarbonate is reabsorbed by 2 distinct processes. The quantitatively more significant process may involve ionic reabsorption of bicarbonate secondary to Na+ reabsorption and a relatively minor part of bicarbonate reabsorption may be secondary to H+ secretion.
Keyword Bicarbonate
Carbonic anhydrase
Tubular reabsorption
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 2 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 1 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Tue, 14 Jun 2016, 14:45:41 EST by System User