PITUITARY FUNCTION IN IDIOPATHIC HÆMOCHROMATOSIS AND CIRRHOSIS OF THE LIVER

Stocks AlanE. and Powell LawrieW. (1972) PITUITARY FUNCTION IN IDIOPATHIC HÆMOCHROMATOSIS AND CIRRHOSIS OF THE LIVER. The Lancet, 300 7772: 298-300. doi:10.1016/S0140-6736(72)92905-4


Author Stocks AlanE.
Powell LawrieW.
Title PITUITARY FUNCTION IN IDIOPATHIC HÆMOCHROMATOSIS AND CIRRHOSIS OF THE LIVER
Journal name The Lancet   Check publisher's open access policy
ISSN 0140-6736
Publication date 1972-08-12
Sub-type Article (original research)
DOI 10.1016/S0140-6736(72)92905-4
Volume 300
Issue 7772
Start page 298
End page 300
Total pages 3
Subject 2700 Medicine
Abstract Testicular atrophy was found in 13 of 23 male patients with idiopathic hæmochromatosis and in 10 of 14 patients with cirrhosis of the liver from other causes. Other indices of gonadal hypofunction were common in both men and women with hæmochromatosis, but only in men with cirrhosis. There was depression of plasma-luteinising-hormone in 44% of 32 patients with hæmochromatosis, but in none of 18 patients with cirrhosis. These and other endocrine studies suggested that generalised depression of pituitary function occurs in hæmochromatosis but not in cirrhosis. Testicular atrophy in hæmochromatosis is probably due to loss of gonadotrophins, in contrast to cirrhosis of the liver, where an imbalance between oestrogens and androgens may have a more direct effect on the testis.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
 
Versions
Version Filter Type
Citation counts: Scopus Citation Count Cited 36 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Tue, 14 Jun 2016, 14:30:01 EST by System User