Effect of calcium ion on the interaction of aldolase with rabbit muscle myofibrils

Harris S.J. and Winzor D.J. (1989) Effect of calcium ion on the interaction of aldolase with rabbit muscle myofibrils. Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular, 999 1: 95-99. doi:10.1016/0167-4838(89)90035-6


Author Harris S.J.
Winzor D.J.
Title Effect of calcium ion on the interaction of aldolase with rabbit muscle myofibrils
Journal name Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular
ISSN 0167-4838
Publication date 1989-11-09
Sub-type Article (original research)
DOI 10.1016/0167-4838(89)90035-6
Volume 999
Issue 1
Start page 95
End page 99
Total pages 5
Subject 1303 Specialist Studies in Education
1304 Biophysics
1312 Molecular Biology
1315 Structural Biology
Abstract A partition equilibrium study has shown calcium ion to be a noncompetitive inhibitor of aldolase adsorption by rabbit muscle myofibrils. This inhibition is interpreted quantitatively in terms of a 10-fold decrease in the intrinsic association constant for the aldolase-myofibril interaction upon Ca2+ binding to either or both of the low-affinity troponin sites associated with regulation of muscle contraction.
Keyword Aldolase-myofibril interaction
Calcium-binding
Muscle myofibril
Troponin
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
 
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