A dose-response study on fenoterol (Berotec) solution by inhalation in asthmatic children

Blackhall M.I., Macartney B. and O'Donnell S.R. (1983) A dose-response study on fenoterol (Berotec) solution by inhalation in asthmatic children. Developmental Pharmacology and Therapeutics, 6 6: 374-380.

Author Blackhall M.I.
Macartney B.
O'Donnell S.R.
Title A dose-response study on fenoterol (Berotec) solution by inhalation in asthmatic children
Journal name Developmental Pharmacology and Therapeutics   Check publisher's open access policy
ISSN 0379-8305
Publication date 1983-01-01
Sub-type Article (original research)
Open Access Status Not yet assessed
Volume 6
Issue 6
Start page 374
End page 380
Total pages 7
Language eng
Subject 2736 Pharmacology (medical)
3000 Pharmacology, Toxicology and Pharmaceutics
Abstract Fenoterol (Berotec) was administered by inhalation, using a Bennett nebulizer, to symptom-free asthmatic children aged 6-13 years. It was demonstrated in a double-blind, crossover trial in 6 children that the improvement in the forced expiratory volume produced by inhalation of a nebulised fenoterol solution was not a placebo effect. Fenoterol (0.1 mg) produced effective bronchodilatation but there was a significant logarithmic dose-response relationship over the dose range tested (0.1-0.8 mg cumulative). There was no effect of the drug on heart rate even with the 0.8 mg dose.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
 
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Created: Tue, 14 Jun 2016, 12:04:28 EST by System User