Resistant hypertension and chronic kidney disease: a dangerous liaison

Wolley, Martin J. and Stowasser, Michael (2016) Resistant hypertension and chronic kidney disease: a dangerous liaison. Current Hypertension Reports, 18 36: 1-9. doi:10.1007/s11906-016-0641-x


Author Wolley, Martin J.
Stowasser, Michael
Title Resistant hypertension and chronic kidney disease: a dangerous liaison
Journal name Current Hypertension Reports   Check publisher's open access policy
ISSN 1534-3111
1522-6417
Publication date 2016-05-01
Year available 2016
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1007/s11906-016-0641-x
Open Access Status Not Open Access
Volume 18
Issue 36
Start page 1
End page 9
Total pages 9
Place of publication Philadelphia, PA United States
Publisher Springer Healthcare
Language eng
Abstract Treatment-resistant hypertension is an increasingly recognised problem and is markedly over-represented in patients with chronic kidney disease (CKD). Recent evidence has clarified the heightened risk for both adverse renal and cardiovascular outcomes associated with resistant hypertension, even when blood pressure control is attained. The diagnosis of resistant hypertension in CKD is reliant on accurate blood pressure measurement, and out of office measurements are important due to the high prevalence of masked hypertension in these patients. Treatment strategies include careful dietary measures to restrict sodium intake, and a focus on improving adherence to antihypertensive medications. Medication choices should focus on a sensible foundation and then diuretic titration to combat the salt and volume retention inherent in CKD. In this review, we discuss the epidemiology, pathogenesis and consequences of resistant hypertension in CKD, and then review the optimal diagnostic and management strategies.
Keyword Resistant hypertension
Chronic kidney disease
CKD
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
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