The addition of high magnifying endoscopy improves rates of high confidence optical diagnosis of colorectal polyps

Iwatate, Mineo, Sano, Yasushi, Hattori, Santa, Sano, Wataru, Hasuike, Noriaki, Ikumoto, Taro, Kotaka, Masahito, Murakami, Yoshitaka, Hewett, David G., Soetikno, Roy, Kaltenbach, Tonya and Fujimori, Takahiro (2015) The addition of high magnifying endoscopy improves rates of high confidence optical diagnosis of colorectal polyps. Endoscopy International Open, 3 2: E140-E145. doi:10.1055/s-0034-1391362


Author Iwatate, Mineo
Sano, Yasushi
Hattori, Santa
Sano, Wataru
Hasuike, Noriaki
Ikumoto, Taro
Kotaka, Masahito
Murakami, Yoshitaka
Hewett, David G.
Soetikno, Roy
Kaltenbach, Tonya
Fujimori, Takahiro
Title The addition of high magnifying endoscopy improves rates of high confidence optical diagnosis of colorectal polyps
Journal name Endoscopy International Open   Check publisher's open access policy
ISSN 2364-3722
2196-9736
Publication date 2015-04-01
Year available 2015
Sub-type Article (original research)
DOI 10.1055/s-0034-1391362
Open Access Status DOI
Volume 3
Issue 2
Start page E140
End page E145
Total pages 6
Place of publication Stuttgart, Germany
Publisher Georg Thieme Verlag
Language eng
Abstract Background and study aims: The real-time optical diagnosis of colorectal polyps with high confidence predictions can achieve high levels of accuracy. Increasing the rates of high confidence optical diagnosis can improve the clinical application of real-time optical diagnosis in routine practice. The primary aim of this prospective study was to evaluate whether high magnifying endoscopy improves the rates of high confidence narrow-band imaging (NBI)-based optical diagnosis for differentiating between neoplastic and non-neoplastic colorectal lesions according to the NBI international colorectal endoscopic (NICE) classification.
Formatted abstract
Background and study aims: The real-time optical diagnosis of colorectal polyps with high confidence predictions can achieve high levels of accuracy. Increasing the rates of high confidence optical diagnosis can improve the clinical application of real-time optical diagnosis in routine practice. The primary aim of this prospective study was to evaluate whether high magnifying endoscopy improves the rates of high confidence narrow-band imaging (NBI) – based optical diagnosis for differentiating between neoplastic and non-neoplastic colorectal lesions according to the NBI international colorectal endoscopic (NICE) classification.

Patients and methods: Consecutive adult patients undergoing colonoscopy with a high magnifying (maximum, × 80) colonoscope between April and August 2012 were recruited. The optical diagnosis for each polyp was evaluated during colonoscopy in two consecutive stages by the same endoscopist, who first used NBI with non-magnifying endoscopy (NBI-NME), then NBI with magnifying endoscopy (NBI-ME). A level of confidence was assigned to each prediction.

Results: The analysis included 124 patients (mean age, 56.4 years; male-to-female ratio, 72:52) with 248 polyps smaller than 10 mm. Of the 248 polyps, 210 were 1 to 5 mm in size and 38 were 6 to 9 mm in size; 77 polyps were hyperplastic, 4 were sessile serrated adenomas/polyps, 160 were low grade adenomas, 5 were high grade adenomas, and 2 were deep submucosal invasive carcinomas. The rate of high confidence optical diagnosis when NBI-ME was used was significantly higher than the rate when NBI-NME was used for diminutive (1 – 5 mm) polyps (92.9 % vs 79.5 %, P < 0.001) and for small (6 – 9 mm) polyps (94.7 % vs 84.2 %, P = 0.048).

Conclusion: High magnifying endoscopy significantly improved the rates of high confidence NBI-based optical diagnosis of diminutive and small colorectal polyps.
Keyword Classification
Validation
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2016 Collection
School of Medicine Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 9 times in Thomson Reuters Web of Science Article | Citations
Google Scholar Search Google Scholar
Created: Sat, 19 Mar 2016, 04:47:08 EST by System User on behalf of Learning and Research Services (UQ Library)