Assessment of temperature effect on childhood hand, foot and mouth disease incidence (0–5 years) and associated effect modifiers: a 17 cities study in Shandong Province, China, 2007–2012

Zhu, Lin, Wang, Xianjun, Guo, Yuming, Xu, Jing, Xue, Fuzhong and Liu, Yanxun (2016) Assessment of temperature effect on childhood hand, foot and mouth disease incidence (0–5 years) and associated effect modifiers: a 17 cities study in Shandong Province, China, 2007–2012. Science of the Total Environment, 551-552 452-459. doi:10.1016/j.scitotenv.2016.01.173

Attached Files (Some files may be inaccessible until you login with your UQ eSpace credentials)
Name Description MIMEType Size Downloads

Author Zhu, Lin
Wang, Xianjun
Guo, Yuming
Xu, Jing
Xue, Fuzhong
Liu, Yanxun
Title Assessment of temperature effect on childhood hand, foot and mouth disease incidence (0–5 years) and associated effect modifiers: a 17 cities study in Shandong Province, China, 2007–2012
Journal name Science of the Total Environment   Check publisher's open access policy
ISSN 0048-9697
1879-1026
Publication date 2016-05-01
Sub-type Article (original research)
DOI 10.1016/j.scitotenv.2016.01.173
Open Access Status Not Open Access
Volume 551-552
Start page 452
End page 459
Total pages 8
Place of publication Amsterdam, Netherlands
Publisher Elsevier
Language eng
Subject 2305 Environmental Engineering
2304 Environmental Chemistry
2311 Waste Management and Disposal
2310 Pollution
Abstract Background: Previous studies examining temperature-disease associations of hand, foot and mouth disease (HFMD) mainly focused on a single city. The results demonstrated great heterogeneity. A multi-city study is necessary to better understand temperature risk on the childhood incidence of HFMD and the associated modified factors. Objective: To assess the effect of ambient temperature on childhood HFMD incidence and explore the potential associated effect modifiers in the study area. Methods: Daily morbidity data and meteorological variables of the 17 cities were collected for the period from 2007 to 2012. Distributed lag non-linear model (DLNM) was used to estimate city-specific effects of temperature on HFMD incidence. A multivariate meta-analysis was then applied to pool the estimated city-specific effect. Potential effect modifiers were included in the multivariate meta-regression as meta-predictors. Results: A total of 504,017 childhood HFMD cases were included in the study. The high-incidence period of HFMD was detected in late spring and early summer (April to June). The temperature-disease associations of the 17 cities demonstrated great heterogeneity and the pooled exposure-response curve was an approximately inverted V-shape. Regional indicator, numbers of healthcare institution and annual household income were considered as associated modifiers. Conclusion: Our findings can provide a practical reference for the early warning and intervention strategies of HFMD. Different temperature-disease associations among different regions should be considered when formulating and optimizing public health policy.
Keyword Temperature-disease association
Hand, foot and mouth disease
Child
Multi-city
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
School of Public Health Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 4 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 4 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Tue, 16 Feb 2016, 21:26:31 EST by Yuming Guo on behalf of School of Public Health