[3H]GABA uptake and GABA localization in mucosal endocrine cells of the rat stomach and colon

Krantis A., Tufts K., Nichols K. and Morris G.P. (1994) [3H]GABA uptake and GABA localization in mucosal endocrine cells of the rat stomach and colon. Journal of the Autonomic Nervous System, 47 3: 225-232.

Author Krantis A.
Tufts K.
Nichols K.
Morris G.P.
Title [3H]GABA uptake and GABA localization in mucosal endocrine cells of the rat stomach and colon
Journal name Journal of the Autonomic Nervous System   Check publisher's open access policy
ISSN 0165-1838
Publication date 1994-01-01
Sub-type Article (original research)
Open Access Status Not yet assessed
Volume 47
Issue 3
Start page 225
End page 232
Total pages 8
Subject 2800 Neuroscience
2728 Clinical Neurology
1314 Physiology
Abstract The aim of this study was to characterize the distribution of GABAergic cells in the rat gut mucosa. Thin and/or thick serial sections of segments of rat antrum and distal colon were treated for autoradiographic localization of sites of [3H]GABA (50 nM) high-affinity uptake, or GABA immunoreactivity. Dense accumulations of silver grains were localized to a discrete population of granulated mucosal cells. These appeared to be D-type endocrine cells. These gut regions also displayed strongly GABA-immunoreactive mucosal cells. These results confirm the presence of GABAergic cells in the rat antral mucosa, and reveal that [3H]GABA is accumulated by mucosal endocrine cells in the rat colon.
Keyword Autoradiography
Colon
Electronmicroscopy
Endocrine
GABA
Immunoreactive
Mucosa
Rat
Stomach
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 14 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 13 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Wed, 10 Feb 2016, 18:00:52 EST by Dr Kim Nichols