Uterine oxytocin receptors in an australian marsupial, the brushtail possum, Trichosurus vulpecula

Sernia, C, Garciaaragon, J, Thomas, WG and Gemmell, RT (1990) Uterine oxytocin receptors in an australian marsupial, the brushtail possum, Trichosurus vulpecula. Comparative Biochemistry and Physiology -- Part A: Physiology, 95 1: 135-138. doi:10.1016/0300-9629(90)90021-J


Author Sernia, C
Garciaaragon, J
Thomas, WG
Gemmell, RT
Title Uterine oxytocin receptors in an australian marsupial, the brushtail possum, Trichosurus vulpecula
Journal name Comparative Biochemistry and Physiology -- Part A: Physiology   Check publisher's open access policy
ISSN 0300-9629
Publication date 1990-01-01
Sub-type Article (original research)
DOI 10.1016/0300-9629(90)90021-J
Volume 95
Issue 1
Start page 135
End page 138
Total pages 4
Language eng
Subject 1314 Physiology
1312 Molecular Biology
1303 Specialist Studies in Education
Abstract 1. 1. Oxytocin receptors in the uterus of the brushtail possum (T. vulpecula) were characterized by radioreceptor assay and compared with those of the sheep and rat uterus. 2. 2. A single oxytocin binding site was found with an affinity (Kd) and receptor concentration (Ro) of 3.0 ± 0.8 nmol/1 and 200 ± 60 fmol/mg protein, respectively (SEM; n = 5). The receptor was stable at -20°C; divalent ions were required for optimum binding. 3. 3. Competitive displacement curves with related peptides showed the following order of specificity: vasotocin > oxytoein > mesotocin = arginine-vasopressin = [Thr4, Gly7-oxytocin > lysine-vasopressin = isotocin >[d(CH2)5, D-Phe2, Ile4, Ala9-NH2]-AVP. 4. 4. It was concluded that oxytocin receptors in the possum have similar characteristics to those of placental mammals.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collections: ResearcherID Downloads
Scopus Import - Archived
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 13 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 10 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Sat, 06 Feb 2016, 05:20:11 EST by System User