Gallium-68 PSMA uptake in adrenal adenoma

Law, W Phillip, Fiumara, Frank, Fong, William and Miles, Kenneth A. (2016) Gallium-68 PSMA uptake in adrenal adenoma. Journal of Medical Imaging and Radiation Oncology, 60 4: 514-517. doi:10.1111/1754-9485.12357

Author Law, W Phillip
Fiumara, Frank
Fong, William
Miles, Kenneth A.
Title Gallium-68 PSMA uptake in adrenal adenoma
Journal name Journal of Medical Imaging and Radiation Oncology   Check publisher's open access policy
ISSN 1754-9485
Publication date 2016-08-01
Year available 2015
Sub-type Article (original research)
DOI 10.1111/1754-9485.12357
Open Access Status Not yet assessed
Volume 60
Issue 4
Start page 514
End page 517
Total pages 4
Place of publication Richmond, VIC, Australia
Publisher Wiley-Blackwell Publishing Asia
Language eng
Subject 2730 Oncology
2741 Radiology Nuclear Medicine and imaging
Abstract Gallium-68 (Ga-68) labelled prostate-specific membrane antigen (PSMA) imaging by positron emission tomography (PET) has emerged as a promising tool for staging of prostate cancer and restaging of disease in recurrence or biochemical failure after definitive treatment of prostate cancer. Ga-68 PSMA PET produces high target-to-background images of prostate cancer and its metastases which are reflective of the significant overexpression of PSMA in these cells and greatly facilitates tumour detection. However, relatively little is known about the PSMA expression of benign neoplasms and non-prostate epithelial malignancies. This is a case report of PSMA uptake in an adrenal adenoma incidentally discovered on PET performed for restaging of biochemically suspected prostate cancer recurrence. With the increasing use of PSMA PET in the management of prostate cancer - and the not infrequent occurrence of adrenal adenomas - the appearance of low- to moderate-grade PSMA uptake in adrenal adenomas should be one with which reporting clinicians are familiar.
Keyword Adenoma
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
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