Frontline treatment of epithelial ovarian cancer

Goh, Jeffrey, Mohan, G. Raj, Ladwa, Rahul, Ananda, Sumitra, Cohen, Paul A. and Baron-Hay, Sally (2015) Frontline treatment of epithelial ovarian cancer. Asia-Pacific Journal of Clinical Oncology, 11 Supplement s6: 1-16. doi:10.1111/ajco.12449

Author Goh, Jeffrey
Mohan, G. Raj
Ladwa, Rahul
Ananda, Sumitra
Cohen, Paul A.
Baron-Hay, Sally
Title Frontline treatment of epithelial ovarian cancer
Journal name Asia-Pacific Journal of Clinical Oncology   Check publisher's open access policy
ISSN 1743-7563
Publication date 2015-12-15
Year available 2015
Sub-type Article (original research)
DOI 10.1111/ajco.12449
Open Access Status Not yet assessed
Volume 11
Issue Supplement s6
Start page 1
End page 16
Total pages 16
Place of publication Chichester, West Sussex, United Kingdom
Publisher Blackwell Publishing Ltd
Language eng
Subject 2730 Oncology
Abstract This is a contemporaneous review of the frontline treatment of epithelial ovarian cancer (EOC), specifically on the importance of optimal surgical cytoreductive surgery, the pivotal role of platinum-based adjuvant chemotherapy (which encompasses intraperitoneal and dose-dense regimens) and the emergence of neo-adjuvant chemotherapy. Additionally, the benefit of concurrent and maintenance bevacizumab in the suboptimally debullked stage III and stage IV EOC setting is also reviewed. The article also discusses the increasing importance of prognostic and predictive molecular biomarkers in the future management of EOC.
Keyword Epithelial ovarian cancer
Molecular biomarkers
Molecular targeted therapy cytoreduction surgical procedure
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2016 Collection
School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 5 times in Thomson Reuters Web of Science Article | Citations
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